Non-irritant Non-exothermic Non-toxic Biocompatible
PBT™ Protonated Bioadhesive Technology SureKlot™ patches are bioactive hemostatic dressings. They operate on a unique load-based mucoadhesion mechanism that forms a mechanical barrier over the bleeding site or the entire surface of external wounds.
They stop moderate to severe bleeding from cuts, abrasions, lacerations, punctures, venous or arterial bleeding. These patches are unique in the sense that they adhere to tissues when necessary and come off easily once their work is finished (by irrigating with physiological serum you will break the adhesion bridge).
Another advantage of PBT™ is faster hemostasis due to the electrostatic interaction between the positively charged biopolymer and the negatively charged blood cells. Thanks to its positive charge, the PBT™ biopolymer attracts red blood cells (RBCs) and platelets and traps them in its porous structure, leading to platelet activation and the formation of a powerful blood clot. The combined effect of bioadhesion and a strong blood clot is instant hemostasis. This method of bleeding control is robust enough to work regardless of natural clotting factors. SureKlot™ patches are therefore effective even in patients taking anticoagulant medications. Finally, the enhanced cationic charge provided by the PBT™ biopolymer also imparts strong antimicrobial properties to the material (active antimicrobial barrier) by limiting the entry of external bacteria (muco-adhesion) into the wound site while maintaining a moist environment , favorable to cell proliferation and wound healing.
PBT™ protonated bioadhesive technology
When the SureKlot™ Patch comes into contact with the bleeding site, it ensures strong and rapid hemostasis through mucoadhesion,
by rapidly absorbing blood plasma and concentrating clotting factors at the breach.
Positively charged SureKlot™ will create an electrostatic interaction with moving negatively charged blood cells.The blood cells react to contact with the SureKIotTM Patch and create a hemostatic nail robust.
Mode of action:
The SureKlot™ Patch allows faster hemostasis due to the electrostatic interaction between the positively charged Chitisan biopolymer and the negatively charged blood cells. Thanks to its positive charge, the PBT™ biopolymer attracts red blood cells (RBCs) and platelets and traps them in its porous structure (concentration), which leads to the activation of platelets and the formation of a powerful blood clot. The combined effect of bioadhesion and a strong blood clot is instant hemostasis.
This method of controlling bleeding is robust enough to work regardless of natural clotting factors. PBT™ is therefore effective even in patients taking anticoagulant medications. Finally, the enhanced cationic charge provided by the PBT™ biopolymer also imparts strong antimicrobial properties to the material (antimicrobial barrier) by limiting the entry of external bacteria (muco-adhesion) into the wound site while maintaining a moist, favorable environment. cell proliferation and wound healing.
SureKlot™ patches are recommended for:
Moderate to severe bleeding (arterial and venous), lacerations, abrasions, surgical debridement sites, surface puncture sites, vascular procedure sites and sites involving percutaneous catheters (tubes and pins), traumatic bleeding and surgical, tumor surgery.
Tear the SureKlot™ envelope and remove the patch with sterile gloves.
In surgery: apply the SureKlot™ Patch with even pressure until the dressing adheres to the wound. Never dab the bleeding area with the Patch. Once applied, do not lift or remove the SureKlot™ patch, even to check hemostasis.
On external wounds or surgical debridement: apply the SureKlot™ Patch with even pressure until the Patch adheres to the wound. Be sure to always use a sterile compress between the Patch and your gloves. Apply a secondary dressing if you decide to leave the SureKlot™ Patch in place for up to 24 hours to benefit from all the inherent properties of Chitosan.
The SureKlot™ Patch can be cut, folded and inserted into deep wounds. You can therefore adapt it perfectly to the area of the lesion. It is important that the Patch completely covers the bleeding area. It even works on patients on anticoagulants.
To remove the SureKlot™ patch, irrigate with saline/water solution and peel off gently.
